Try to keep the ingredients in the centre column, and keep hitting that icing with as many striped candies as you can. If the ingredients make their way to the outside columns, you are pretty much in trouble.
Remember to use one of the coconut wheels to destroy the liquorice locks, and another to attack the icing on the bottom. Rolling the wheels create striped candies to destroy the bottom icing and get rid of liquorice locks.
This should make the level easier and then use other combinations to destroy the remaining multilayered icing and liquorice locks. Wrapped candies are useful since they blow up twice.
On a side note, a perfectly positioned wrapped candy + striped candy combination does the job simultaneously.